1988. 9-1992. 7 華東理工大學,生物化學專業,學士學位
1992. 9-1997. 6 中國科學院上海植物生理所,遺傳學,博士學位
1997. 7-2004. 5 美國Rutgers大學Waksman研究所,博士後
2004. 6-2015.11 上海大學,生命科學學院,教授
2015.12-至今 中國農業大學,爱游戏官网app,教授
榮譽稱號:
2006年 教育部新世紀優秀人才計劃
2014年 國家傑出青年科學基金
2015年 國家百千萬人才工程,有突出貢獻中青年專家
2016年 國務院政府特殊津貼
玉米籽粒發育的分子調控網絡機制:籽粒是玉米的主要儲藏器官,也是產量和品質的最終體現。通過對玉米籽粒發育過程中關鍵基因的克隆和功能分析,揭示玉米籽粒發育的分子調控機制。通過玉米籽粒發育中關鍵轉錄因子及其基因調控網絡的解析,構建玉米籽粒發育的分子調控網絡,從系統生物學角度闡明玉米籽粒的發育過程。
玉米蛋白品質形成的分子機制和育種改良:玉米作物最主要的飼料作物,蛋白品質是首要的品質性狀。通過對玉米籽粒儲藏蛋白的轉錄、翻譯、加工和儲藏等多個過程的深入研究,解析玉米蛋白品質形成的分子機制。利用CRSIPR基因編輯、合成生物學等技術手段,改造玉米籽粒內源儲藏蛋白系統,並引入外源儲藏蛋白,實現對玉米蛋白品質的育種改良。
1. 國家自然科學基金,重大研究計劃集成項目,項目編號:91935303, 玉米產量和品質關鍵性狀遺傳網絡構建,執行年限:2020年1月-2021年12月,合同經費:1000萬,主持
2. 國家自然科學基金,重點項目,項目編號:31730065,玉米醇溶蛋白轉錄因子Opaque2的翻譯後修飾調控研究,執行年限:2018年1月-2022年12月,合同經費:315萬,主持
3. 國家自然科學基金,重大研究計劃集成項目,項目編號:91635303,玉米粒重的多基因調控網絡解析,執行年限:2017年1月-2018年12月,合同經費:135萬,參加
4. 科技部國家重點研發計劃,項目編號:2016YFD0101000,玉米產量、品質性狀的功能基因與調控網絡,執行年限:2016年7月-2020年12月,合同經費:104萬,參加
5. 國家傑出青年科學基金,課題編號 31425019,玉米分子遺傳學,2015年1月-2019年12月,400萬,主持
6. 科技部973計劃子課題,課題編號2014CB138204,玉米品質性狀關鍵基因的克隆和功能分析,2014年1月-2018年12月,230萬,子課題負責
7. 國家自然科學基金重大研究計劃重點項目,課題編號91335208,玉米籽粒發育關鍵基因的生物學功能分析,2014年1月-2016年12月,300萬,主持
1. He Y, Yang Q, Yang J, Wang YF, Sun X, Wang S, Qi W, Ma Z and Song R* (2021). shrunken4 is a mutant allele of ZmYSL2 that affects aleurone development and starch synthesis in maize. Genetics. doi: 10.1093/genetics/iyab070. Online ahead of print.
2. Dai D, Ma Z and Song R* (2021) Maize endosperm development. J Integr Plant Biol. 63(4): 613-627.
3. Dai D, Ma Z and Song R* (2021) Maize kernel development. Mol Breeding. 41:2.
4. Dai D, Jin L, Huo Z, Yan S, Ma Z, Qi W and Song R* (2020) Maize pentatricopeptide repeat protein DEK53 is required for mitochondrial RNA editing at multiple sites and seed development. J Exp Bot. 71(20): 6246-6261.
5. Li C, Qi W, Liang Z, Yang X, Ma Z and Song R* (2020) A SnRK1-ZmRFWD3-Opaque2 signaling axis regulates diurnal nitrogen accumulation in maize seeds. Plant Cell. 32(9): 2823-2841.
6. Li C and Song R* (2020) The regulation of zein biosynthesis in maize endosperm. Theor Appl Genet. 133(5): 1443-1453.
7. Liang L, Zhou L, Tang Y, Li N, Song T, Shao W, Zhang Z, Cai P, Feng F, Ma Y, Yao D, Feng Y, Ma Z, Zhao H*, Song R* (2019) A sequence-indexed Mutator insertional library for maize functional genomics study. Plant Physiol. 181(4): 1404-1414.
8. Wang G, Fan W, Ou M, Wang X, Qin H, Feng F, Du Y, Ni J, Tang J, Song R* and Wang G* (2019) Dek40 encodes a PBAC4 protein required for 20S proteasome biogenesis and seed development. Plant Physiol. 180(4): 2120-2132.
9. Qi W, Lu L, Huang S and Song R* (2019) Maize Dek44 encodes mitochondrial ribosomal protein L9 and is required for seed development. Plant Physiol. 180(4): 2106-2119.
10. Dai D, Tong H, Cheng L, Peng F, Zhang T, Qi W and Song R* (2019) Maize Dek33 encodes a pyrimidine reductase in riboflavin biosynthesis essential for oilbody formation and ABA biosynthesis during seed development. J Exp Bot. 70(19): 5173-5187.
11. Zhu C, Jin G, Fang P, Zhang Y, Feng X, Tang Y, Qi W and Song R* (2019) Maize pentatricopeptide repeat protein DEK41 affects cis-splicing of mitochondrial nad4 intron 3 and seed development. J Exp Bot. 70(15): 3795-3808.
12. Zuo Y, Feng F, Qi W and Song R* (2019) Dek42 encodes an RNA binding protein that affects alternative pre-mRNA splicing and maize kernel development. J Integr Plant Biol. 61(6): 728-748.
13. He Y, Wang J, Qi W and Song R* (2019) Maize Dek15 encodes the cohesin-loading complex subunit SCC4 and is essential for chromosome segregation and kernel development. Plant Cell. 31(2): 465-485.
14. Li C, Yue Y, Chen H, Qi W and Song R* (2018) The ZmbZIP22 transcription factor regulates 27-kD γ-zein gene transcription during maize endosperm development. Plant Cell. 30(10): 2402-2424.
15. Feng F, Qi W, Lv Y, Yan S, Xu L, Yang W, Yuan Y, Chen Y, Zhao H and Song R* (2018) Opaque11 is a central hub of the regulatory network for maize endosperm development and nutrient metabolism. Plant Cell. 30(2): 375-396.
16. Dai D, Luan S, Chen X, Wang Q, Feng Y, Zhu C, Qi W and Song R* (2018) Maize Dek37 encodes a P-type PPR protein that affects cis-splicing of mitochondrial nad2 intron 1 and seed development. Genetics. 208(3): 1069-1082.
17. Wang G, Zhong M, Shuai B, Song J, Zhang J, Han L, Ling H, Tang Y, Wang G* and Song R* (2017) E+ subgroup PPR protein defective kernel 36 is required for multiple mitochondrial transcripts editing and seed development in maize and Arabidopsis. New Phytol. 214(4): 1563-1578.
18. Qi W, Tian Z, Lu L, Chen X, Chen X, Zhang W and Song R* (2017) Editing of mitochondrial transcripts nad3 and cox2 by Dek10 is essential for mitochondrial function and maize plant development. Genetics. 205(4): 1489-1501.
19. Qi W, Yang Y, Feng X, Zhang M and Song R* (2017) Mitochondrial function and maize kernel development requires Dek2, a Pentatricopeptide Repeat protein involved in nad1 mRNA splicing. Genetics. 205(1): 239-249.
20. Wang G, Wang G, Wang J, Du Y, Yao D, Shuai B, Han L, Tang Y and Song R* (2016) Comprehensive proteomic analysis of developing protein bodies in maize (Zea mays) endosperm provides novel insights into its biogenesis. J Exp Bot. 67(22): 6323-6335.
21. Chen X, Feng F, Qi W, Xu L, Yao D, Wang Q and Song R* (2017) Dek35 encodes a PPR protein that affects cis-splicing of mitochondrial nad4 intron 1 and seed development in maize. Mol Plant. 10(3): 427-441.
22. Qi W, Zhu T, Tian Z, Li C, Zhang W and Song R* (2016) High-efficiency CRISPR/Cas9 multiplex gene editing using the glycine tRNA-processing system-based strategy in maize. BMC Biotechnol. 16(1): 58
23. Yao D, Qi W, Li X, Yang Q, Yan S, Ling H, Wang G, Wang G and Song R* (2016) Maize opaque10 encodes a cereal-specific protein that is essential for the proper distribution of zeins in endosperm protein bodies. PLoS Genet. 12(8): e1006270.
24. Qiao Z, Qi W, Wang Q, Feng Y, Yang Q, Zhang N, Wang S, Tang Y and Song R* (2016) ZmMADS47 regulates zein gene transcription through interaction with Opaque2. PLoS Genet. 12(4): e1005991
25. Sun X, Qi W, Yue Y, Ling H, Wang G and Song R* (2016) Maize ZmVPP5 is a truncated vasuole H+-PPase that confers hypersensitivity to salt stress. J Integr Plant Biol. 58(6): 518-51.
26. Qi W, Zhu J, Wu Q, Wang Q, Li X, Yao D, Jin Y, Wang G, Wang G and Song R* (2016) Maize reas1 mutant stimulates ribosome use efficiency and triggers distinct transcriptional and translational responses. Plant Physiol. 170(2): 971-88.